WHEN: Monday, October 2, 2017
WHERE: Duquesne University
RSVP BY: Monday, September 25, 2017
Dinner reservations are no longer being accepted.
5:00 PM Social Hour: Power Center Ballroom
6:00 PM Dinner: Power Center Ballroom
Business Meeting: Power Center Ballroom
Technical Meeting: Power Center Ballroom
Student Affiliate Meeting: Shepperson Suite
Gregg E. Homanics, Ph.D., Professor of Anesthesiology, Neurobiology, and Pharmacology & Chemical Biology, University of Pittsburgh
“Gins of the Fathers: Can Alcoholism be Epigenetically Inherited?”
Transmission of DNA variants from parent to offspring (i.e., Mendelian inheritance) has been the generally accepted explanation for the familial nature of alcoholism. However, despite decades of intense effort, only a few DNA variants have been identified and they only explain a small fraction of alcoholism heritability. The search for the “missing heritability” has reinvigorated interest in the once discounted theory that traits acquired during an individual’s lifetime can be transmitted across generations. Dr. Homanics will challenge the dogmatic Mendelian view of inheritance by focusing on investigations of transgenerational epigenetic inheritance (a.k.a., soft inheritance). He will address the provocative hypothesis that alcohol or stress exposure produce enduring epigenetic effects that can be passed through the germline, influence the epigenetic program of descendants, and ultimately impact alcohol drinking and behavioral responses to alcohol.